
Three NIH clinical trials in progress—one trial now in Phase 2

Q2i’s leading edge technology provides remote patient engagement and management tools that empower healthcare teams to improve the success of their Medication-Assisted Treatment (MAT) program.
Q2i’s solutions comprise healthcare team portals and patient mobile applications. We provide decision support software through data-rich, patient-centric, unified dashboards. Our technology includes predictive analytics (including AI and ML), telehealth and reward based solutions that increase patient engagement, adherence to treatment plans, connectedness and support, resulting in:
Better outcomes
Improved ownership and adherence to treatment plans
and increased program retention
Timely interventions
Trending issues immediately flagged for attention
Focus on at-risk patients
Outliers identified and patients managed by exception
Results Using Q2i Technology
Improves Patient Engagement
- Patient Portals (SUD) 11.2%
- Q2i’s Patient Mobile App 85%
Increases Patient Adherence to Treatment Plan*
- National MAT Average 50%
- Q2i’s OARS Technology 92%
* Based on Urine Toxicology Results (Opioid Negative)
%
Extra Provider Revenue
Missed appointments lead to lost revenue for providers. Patients using OARS attend more appointments than the national average for MAT patients by >32%.
UCLA Phase 1 Responses
A recent study of OARS in a primary care setting found that both primary care providers and MOUD patients felt that:
- OARS is easy to use
- OARS improves patient-provider communication
- OARS improves patient engagement in treatment
Provider Quotes
Ease of Use
- “It was easy, user friendly, very easy to adapt with.” (1017)
- “Very user friendly I have to say. Like really, it was very simple to navigate, I am not IT savvy at all. If I tell you it was easy, it was easy.” (1009)
- “The software was really easy to use.” (1050)
- “Yeah. I think it was pretty easy to learn and pretty straightforward.” (1046)
Communication
- “I think the first big thing is that, it really puts the patient in the driver’s seat. I definitely liked the direct patient communication.” (1007)
- “What I really liked is how I knew what was going on in my patient’s life. I feel like it allowed me to give more informed care” (1004)
- ”(Patients) liked being able to look at the phone and connect with me. We do have a patient portal, but it’s cumbersome, and it’s hard to get access through your phone. You can, but it’s hard. So, I think that that opened that communication line.” (1048)
- “Well, I think it has the potential to impact in a very positive way, but if the patient is engaged and they’re part of it. Because if something’s going on in their lives and they journal about it, you can potentially reach out to them, and then that may create a new direction of treatment, or in addition to treatment.”(1044)
Engagement
- “I absolutely loved the journal and also being able to see all the metrics that we want to follow up with these patients in terms of their visits and UDS and stuff like that we could actually see on one page.” (1009)
- “It gave a more holistic approach. You can see all aspects of their treatment and see like how compliant they are in all aspects.” (1011)
- “I think it will give me a lot more information and insight about the patient, instead of just that one interview at the beginning. That’s basically what I base on. It’s kind of like, instead of, you know, horse blind kind of front view, I will get multiple angles and dimension, based on the information that OARS can provide me from the patient. I think that’s a tool part that I’m looking for, to help me with my MAT patient management.” (1065)
- “It just made it easier to understand where she was in terms of her recovery since. And so I was really happy with them and she was really surprised that it has helped her. That’s where I think it helped.” (1050)
Patient Quotes
Ease of Use
- “I just got right into it. It was pretty self-explanatory. It was one of the easiest apps I’ve used.” (1035)
- “I’ve found the app to be very user friendly.” (1034)
- “The whole app is easy to use. I’m very ‘tech savvy’, so I didn’t have any problems at all. A lot of people, who aren’t ‘tech savvy’, would still have no problem.” (1057)
- “As for using the app itself, it was easy to use it. It seemed to cover everything that was needed in terms of treatment.” (1061)
Communication
- “It allowed me to have more direct conversation with them and allowed me to kind of get a better understanding of how they feel about my progress.” (1042)
- “I think that with the OARS app, I have a better relationship, a patient-doctor relationship, where my doctor has a better understanding of who I am, where I’m at, and why I’m in this state that I’m in with everything that’s going on. I think it changed it dramatically in a very, very positive way.” (1022)
- “Yeah, definitely. Definitely. I could see if I were to have those desires to maybe slip up a little bit, that it would be that much easier to get in contact with somebody and help maybe talk me off the ledge a little bit.” (1058)
- “I think it made my interactions with my doctor a lot better, because you feel that connectivity to them number one, when you have the app. And then also you’re more self-aware while you’re using the app.” (1062)
Engagement
- “I really like the journaling. I really enjoy that part because it gives me a more sense of what’s going on with myself. But it’s not even just about me, but it gives my doctor a chance to kind of see what’s going on with me when I might see her once a month and you try to tell somebody what’s going on in that timeframe and it’s kind of hard” (1022)
- “The journaling portion of it is definitely my favorite part of it. It gives me a platform to be able to jot down any notes, anything, how I’m feeling, things like that, and that is awesome.” (1025)
- “Anything that makes managing opioid dependence easier, I am all for. I highly recommend this app for doing that. The one thing that is left out of opioid dependency management a lot is the humanity in it. And this allows more convenience for the patient rather than being demanding of the patient. And I think that’s a really big deal and I applaud y’all for doing it.” (1061)
- “Writing in my journal, it’s harder for me to talk to my wife than it is for me to go in this journal and write and express my feelings. So, it helps a lot. (1053)
- “It was good because it made me figure out that I might not be at the right dosage and that certain journal entriesprovoked thought about maybe I was needing to get more medications, so I think it was extremely helpful. (1055)
100% Cloud, ready-to-go
Modern User Interface
Customizable Branding
Flexible and Scalable

HIPAA Compliant
Solutions
This extended connection and support fosters conditions for:
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CASA enables providers to regularly deliver educational and motivational content including reinforcement of relapse prevention strategies direct to the CASA powered mobile app.
The peer-to-peer messaging component helps build and maintain a network of sober friends with other alumni of the clinic and stay connected to others who relate to similar experiences and challenges.
Bari-Well empowers bariatric programs to better manage their patient populations. Bari-Well supports patients with pre and post surgery treatment plans in order to successfully achieve goals of long-term weight-loss.
Bari-Well provides useful tools to help providers manage and support their patients throughout all stages of the continuum of care.
About Q2i
Our Mission
Our mission is to design, develop, and supply the most advanced technologies that enable care teams to improve the success rate of their Substance Use Disorder treatment programs.
Our Vision
Our vision is to drive innovation in order to increase the success and availability of treatment so that everyone seeking recovery from Substance Use Disorder can obtain the treatment they need.
About
Q2i is a software as a service HealthTec company, specializing in developing applications that support recovery from OUD/SUD. Q2i was formed in 2016 as a result of the devastation occurring in our local communities caused by the opioid epidemic and to work to design technology that supports and improves recovery and help save lives.
Q2i collaborates with multidisciplinary healthcare teams, providers and payers to understand and then realize unmet technology needs. We facilitate improvements in patient care by supporting patients with their treatment plans through better connection and information exchange with their healthcare teams.
Q2i develops technology that assists health care providers in achieving the IHI quadruple aim of improving the patient experience of care (including quality and satisfaction), improving the health of populations, reducing the per capita cost of health care and improved clinician experience.
Contingency Management
Contingency Management (CM) is a reward-based intervention built on the principles of operant conditioning to promote behavior change and reinforce positive behaviors. CM delivers tangible monetary-based rewards contingent upon targeted outcomes or behaviors.
CM has demonstrated efficacy for improving abstinence and other substance use disorder (SUD) treatment outcomes in a diverse range of treatment populations and settings.
Q2i has partnered with Dr. Sheila M. Alessi, Ph.D. from the University of Connecticut. Dr. Alessi and her colleagues at UConn are experts in the field of contingency management. Their goal is to bring CM techniques from research to practice to improve outcomes for OUD/SUD patients.
Difficulties with traditional CM programs include the requirement for intensive hands-on management and oversight to maintain program fidelity. This requires highly trained staff to manage supervision and additional staff to manage the backend operation, such as purchasing of rewards and accounting.
Q2i’s solutions overcome these difficulties by digitizing and automating traditional contingency management and seamlessly integrating it into the cutting-edge Opioid Addiction Recovery Support (OARS) technology. OARS with CM addresses all long-term sustainability challenges while maintaining program fidelity.
OARS with CM, a mobile technology-enabled contingency management program, is a significant scientific and clinical advancement to improve treatment for OUD, SUD, and MAT programs.
Easy, Secure Video Telehealth
OARS has in-built secure, encrypted, HIPAA-compliant Telehealth video. The Care Team can schedule and run one-to-one or group Telehealth sessions directly from their OARS dashboard. Patients can easily and conveniently access sessions from within their OARS mobile app. This keeps all their treatment support in one place and has the added benefits of the OARS calendar of appointments, and alerts for upcoming sessions, making them easy to manage.
Academic Partners/Clinical studies
NIH/National Institute of Drug Abuse funded clinical studies in progress with Q2i’s academic partners

Reward Based Technology to improve opioid use disorder treatment initiation after an ED visit
Increasing the demand and reach of effective Medication Assistance Treatment (MAT) for opioid use disorder (OUD) is critical to decreasing OUD associated morbidity, mortality, and economic consequences. The technology breakthrough to be studied in this project will give individuals with OUD access to a smartphone application designed to help support initiation and adherence with MAT treatment regimens through patient-oriented educational and monitoring features, as well as a new evidence-based reward function shown in other research to promote treatment adherence, improve abstinence, and improve other health outcomes. The intervention will aim to facilitate the entire treatment trajectory, starting with initial transition from an acute care setting to outpatient MAT initiation and continuing through successful transition to maintenance.
NIH/NIDA Grant Number:
1R42DA049448-01


Technology Improving Medication-Assisted Treatment in Primary Care
With over 72,000 overdose deaths in 2017, of which 47,600 are attributable to opioid overdose, the opioid epidemic has become North America’s most widespread behavioral public health problem. Medication assisted treatment (MAT) for opioid use disorder (OUD) is highly efficacious. The Opioid Addiction Recovery Support (OARS) comprises of a healthcare team portal connected to a patient mobile application, to provide opioid related education, promote connectedness with clinicians, and track MAT treatment progress. This STTR Fast Track proposal will conduct interviews with patients that will inform optimal design of OARS and utilize a “stepped wedge” effectiveness design to assess the effectiveness of OARS in improving opioid agonist treatment outcomes in primary care settings and evaluate sustainability and return on investment.
NIH/NIDA Grant Number:
1R42DA050398-01


Digital Health Technology Improving Successful Reintegration of Recently Released Justice-Involved Individuals with Substance Use Disorders
Of the 2 million individuals that are confined nationwide 10,000 are released weekly with inadequate support solutions that comprehensively address social determinants of health resulting in a high recidivism rate. The lack of support can significantly affect health outcomes, especially for recently released justice-involved individuals with substance use disorder (SUD). Digital health technology can help recently released individuals navigate and adapt to their new environment. Technology makes it possible to provide localized support – such as access to location-specific information about risk reduction, housing, accessing medical care, SUD treatment programs and availability, and support groups – that is not available through traditional mechanisms. It transforms support services from fragmented, disparate services to centralized, one-stop shopping that is available 24/7 for people in need.
NIH/NIDA Grant Number:
1R41DA051156-01
Leadership Team

Steven Jenkins
CEO

Gerald A. Kraines, M.D.
CMO

Tony McNamara
CTO

Monica Strunk
Director, Grants and Strategic Partnerships
Medical Advisory Board
Q2i’s Medical Advisory Board provides in-depth subject matter expertise across a broad spectrum of healthcare delivery. This diverse composition provides a strong group dynamic providing insight and scientific direction. This ensures Q2i’s solutions not only improves patient outcomes and helps health systems and payers create value but that we go beyond traditional clinical efficacy to capture newer patient-focused considerations and impact the effectiveness and efficiency of care delivered under new value-based performance systems.

Sara M. Bolton
M.D.

Gary Chinman
M.D

Guy Slater
FRCS

Jeremy Vigneault
PT, MSPT, OCS, Cert. MDT

Jennifer Davenport
MD, MHA, FSCAI

P. Elizabeth Thomas
MD
Q2i in the News
April 28, 2020
Q2i Awarded NIH/NIDA Grant to Develop and Evaluate Digital Technology to Improve Successful Community Reintegration of Recently Released Justice-Involved Individuals With Substance Use Disorders
Jan 7, 2020
Q2i Awarded NIH/NIDA Grant to Develop and Evaluate Digital Technology to Improve Medication-Assisted Treatment in Primary Care
Oct 17, 2019
Sept 4, 2019
Feb 6, 2019
Jan 8, 2019
Nov 15, 2018
Oct 9, 2018
Sep 20, 2018
Sep 6, 2018
April 24, 2018
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Mar 22, 2018
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Mar 8, 2018
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Jan 16, 2018
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Dec 29, 2017
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August 24, 2017
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July 18, 2017
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Contact Q2i
(P) 617.812.2602
1660 Soldiers Field Rd.
Brighton, MA 02135